Journal article
ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide
PM Thompson, EL Dennis, BA Gutman, DP Hibar, N Jahanshad, S Kelly, JL Stein, CD Whelan, OA Andreassen, A Arias-Vasquez, CE Bearden, PS Boedhoe, OL van den Heuvel, DJ Veltman, RM Brouwer, MA de Reus, HEH Pol, MP van den Heuvel, RL Buckner, JK Buitelaar Show all
Neuroimage | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2017
Abstract
In this review, we discuss recent work by the ENIGMA Consortium (http://enigma.ini.usc.edu) – a global alliance of over 500 scientists spread across 200 institutions in 35 countries collectively analyzing brain imaging, clinical, and genetic data. Initially formed to detect genetic influences on brain measures, ENIGMA has grown to over 30 working groups studying 12 major brain diseases by pooling and comparing brain data. In some of the largest neuroimaging studies to date – of schizophrenia and major depression – ENIGMA has found replicable disease effects on the brain that are consistent worldwide, as well as factors that modulate disease effects. In partnership with other consortia includ..
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Grants
Awarded by National Institutes of Health
Funding Acknowledgements
This work was supported in part by a Consortium grant (U54 EB 020403) from the NIH Institutes contributing to the Big Data to Knowledge (BD2K) Initiative, including the NIBIB. Funding for individual consortium authors is listed in Hibar et al., Nature, 2015 and in other papers cited here. This paper was collaboratively written on Google Docs by all authors, over a period of several weeks. We thank Josh Faskowitz for making Fig. 3, the ENIGMA "roadmap".